The Flame Retardants, Polybrominated Diphenyl Ethers, Are Pregnane X Receptor Activators

The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators.

Polybrominated diphenyl ethers (PBDEs) are used as flame retardants and are universally present in the environment. An exponential increase in PBDE concentrations in the U.S. population have been reported over the last 3 decades. PBDEs 47 (tetraBDE) and 99 (pentaBDE) are the most commonly detected PBDE congeners in the environment and in human samples. PBDE209 (decaBDE) is the only remaining PB...

Polybrominated diphenyl ethers (PBDEs) are manufactured as additive flame retardants in the production of polyurethane foams,

Introduction. Polybrominated diphenyl ethers (PBDEs) are manufactured as additive flame retardants in the production of polyurethane foams, textiles and plastics. PBDEs are persistent, lipophilic compounds that bioaccumulate through to the highest levels of the food chain (e.g., Lindberg et al., 2004). Recent reports have demonstrated that avian populations are subject to PBDE bioaccumulation b...

Neonatal Developmental Neurotoxicity of Brominated Flame Retardants, the Polybrominated Diphenyl Ethers (PBDEs)

Occupational Exposure to Brominated Flame Retardants with Emphasis on Polybrominated Diphenyl Ethers

Brominated flame retardants (BFRs) are a diverse group of chemicals, which are used to slow down or inhibit the development of fires. BFRs are incorporated into a wide range of consumer products that are considered as potential fire hazards, such as TV-sets, household appliances, computers, and textiles. The production and use of BFRs is extensive and consists of mainly tetrabromobisphenol A (T...

Polybrominated diphenyl ethers (PBDEs) and alternative brominated flame retardants in air and seawater of the European Arctic.

The spatial distribution of polybrominated diphenyl ethers (PBDEs) and several alternative non-PBDE, non-regulated brominated flame retardants (BFRs) in air and seawater and the air-seawater exchange was investigated in East Greenland Sea using high-volume air and water samples. Total PBDE concentrations (Ó₁₀PBDEs) ranged from 0.09 to 1.8 pg m⁻³ in the atmosphere and from 0.03 to 0.64 pg L⁻¹ in...